Trichomonas vaginalis
Trichomoniasis is caused by a parasite called Trichomonas vaginalis.1
It is transmitted sexually through penis-to-vagina intercourse or vulva-to-vulva (the genital area outside the vagina) contact with an infected partner.1 Once acquired, the organism attaches itself to cells that line the urogenital tract, typically infecting the vagina in women or the urethra in men.1,2
While men normally get trichomoniasis from an infected woman, women can get trichomoniasis from sexual contact with an infected partner of either sex.1
Trichomoniasis risk factors
Certain people may be at a higher risk of getting Trichomoniasis.3,4 You could be at risk if you:
- Have multiple sex partners
- Are African-American
- Have bacterial vaginosis
- Have a history of previous STDs
If you think you're at risk of contracting trichomoniasis, or you're suffering from any symptoms, talk to your doctor or healthcare professional. He or she can diagnose the infection and prescribe the treatment you need.
Important Safety Information
WARNING: POTENTIAL RISK FOR CARCINOGENICITY
Carcinogenicity has been seen in mice and rats treated chronically with metronidazole, another nitroimidazole agent. Although such data have not been reported for tinidazole, the two drugs are structurally related and have similar biologic effects. Its use should be reserved for the conditions described in INDICATIONS AND USAGE.
Contraindications
- Prior history of hypersensitivity to tinidazole or other nitroimidazole derivatives
- First trimester of pregnancy
- Nursing mothers, unless breast-feeding is interrupted during tinidazole therapy and for 3 days following the last dose
Warnings and Precautions
- Seizures and neuropathy have been reported. Discontinue Tindamax if abnormal neurologic signs develop
- Vaginal candidiasis may develop with Tindamax and require treatment with an antifungal agent
- Use Tindamax with caution in patients with blood dyscrasias. Tindamax may produce transient leukopenia and neutropenia
Adverse Reactions
Most common adverse reactions for a single 2 g dose of tinidazole (incidence >1%) are metallic/bitter taste, nausea, weakness/fatigue/malaise, dyspepsia/cramps/epigastric discomfort, vomiting, anorexia, headache, dizziness and constipation. To report SUSPECTED ADVERSE REACTIONS, contact Mission Pharmacal Company at 1-800-298-1087 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch
This material is intended to provide basic information. Patients should discuss all medical advice, diagnosis, and treatment with their healthcare provider.
Please see full Prescribing Information
- Trichomoniasis CDC Fact Sheet [Internet]. CDC; 2007 Dec [accessed 2008 Jul 18]. Available from: http://www.cdc.gov/STD/Trichomonas/Trichomoniasis-Fact-Sheet.pdf
- Lehker MW, Sweeney D. Trichomonad invasion of the mucous layer requires adhesins, mucinases, and motility. Sex Transm Infect. 1999 Aug;75(4):231-8.
- Sobel JD. Vaginitis. N Engl J Med. 1997 Dec 25;337(26):1896-903.
- Heller DS, Maslyak S, Skurnick J. Is the presence of Trichomonas on a Pap smear associated with an increased incidence of bacterial vaginosis? J Low Genit Tract Dis. 2006 Jul;10(3):137-9.
Websites
For Health Professionals
Only Tindamax® is approved to treat both bacterial vaginosis and trichomoniasis (TV).
Clinical Insight
Oral vs vaginal cream therapy: Patient preference for oral dosing is demonstrated to be 84%. More»
Beyond BV
Tindamax® may be prescribed for other infections including:
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